College GameDay is back in the 'Bus this weekend for a B1G matchup. No. 7 Penn State takes on No. 3 Ohio State in Columbus on Saturday, October 21 noon ET. You can watch it on FOX as part of the network's Big Noon Kickoff. 

Saturday will be the 23rd time College GameDay comes to Columbus. That's more times than any other city or school has hosted. Ohio State also leads in all-time appearances at 58. The Buckeyes are 39-18 across previous appearances.

This is the second time this season College GameDay was on hand for an Ohio State game, after setting up shop in South Bend on September 16. The Buckeyes topped the Fighting Irish on the final play of one of the best college football games this season. Penn State vs. Ohio State is also the most frequent matchup in GameDay history, being featured for the 12th time on Saturday.

If you're headed to the University District to tailgate, watch or attend the game, check out our Ohio State Game Day Guide for tips and suggestions.